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Longevity

Live longer. Live well for longer.

Longevity is no longer only about adding years. It is about keeping the energy, strength and independence to enjoy them.

Illustrative AI-generated portrait of the same woman at different ages
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How we age is shaped by more than years. Move to see the years change.
Lifespan and healthspan

The gap between living long and living well.

Lifespan is how long you live. Healthspan is how long you live in good health. For most people, the two are not the same.

9.6 years

Estimated global gap between life expectancy and healthy life expectancy in 2020.1

1 in 5

Singapore citizens aged 65 or older in 2025 (20.7%), rising to an estimated 23.9% by 2030.3

2.1 billion

People aged 60 and over projected worldwide by 2050, up from about 1.2 billion in 2025.2

The goal of modern longevity science is often described as the compression of morbidity: shortening the time spent in poor health at the end of life, so more of life is lived with vitality.

Chronological and biological age

Two numbers. Two different stories.

Chronological age

Counted in years

The time since you were born. Fixed, predictable and the same for everyone who shares your birthday.

Biological age

Measured in the body

An estimate of how your body systems are aging, based on clinical, physiological, metabolic or molecular measures. The idea has been discussed in science since the 1940s.

What shapes biological age

  • Genetics and family history
  • Sleep, nutrition and physical activity
  • Stress, smoking and alcohol
  • Environment and long-term health conditions

How to read it

Different tests look at different signals, from blood markers and physical function to patterns on DNA, so they can give different results. A biological age estimate is not a diagnosis or a prediction of lifespan. Its value is as a baseline: a way to see your trend over time and review what is working.

From anti-aging to healthy aging

Beyond appearance. Toward how you feel and function.

Anti-aging once meant looking younger. Today, the science of aging studies why the body changes over time and how to support healthy function for longer.

01

Aging is shaped

Researchers increasingly view aging as a set of biological processes that lifestyle and environment can influence.

02

Daily habits matter most

Sleep, a balanced diet, regular movement and managing stress remain the foundation. Nothing replaces them.

03

Nutrition can support

Some nutrients, including AKG, are being studied for their role in healthy aging. Research is developing.

Where AKG fits

A decade of AKG research.

AKG is a natural metabolite that declines with age. That has made it a subject of growing interest in aging biology.

  1. 2014

    Early laboratory findings

    Researchers at UCLA reported in Nature that AKG extended lifespan in a small roundworm.4

  2. 2020

    Studies in mice

    A study in Cell Metabolism found that middle-aged mice given Ca-AKG spent less of their lives frail.5

  3. Now

    Human research

    Human studies are at an early stage, and a randomized controlled trial in adults is underway.6

This research used AKG in different forms and settings. It did not test SDAI BioAge™ Core and is shared as background only.

Your next step

Start your journey to healthier years.

SDAI BioAge™ Core: patented controlled-release Ca-AKG, a daily choice for healthier years.

References

  1. World Health Organization. Healthy life expectancy (HALE) estimates, 2020.
  2. United Nations Department of Economic and Social Affairs. World Population Prospects 2024.
  3. National Population and Talent Division (NPTD), Singapore. Population trends, 2025.
  4. Chin RM, Fu X, Pai MY, et al. The metabolite alpha-ketoglutarate extends lifespan by inhibiting the ATP synthase and TOR. Nature. 2014;510(7505):397-401.
  5. Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice. Cell Metabolism. 2020;32(3):447-456.
  6. Sandalova E, et al. Middle-aged adults alpha-ketoglutarate supplementation and biological age (ABLE): study protocol for a randomized controlled trial. GeroScience. 2023.
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